Variola minor virus, also known as the monkeypox virus, is a contagious virus that causes a smallpox-like disease in humans. Synonyms for this virus include orthopoxvirus, alastrim, Cuban itch, and West African clade. In addition to these technical terms, the virus is also commonly referred to as monkeypox, due to its origin in monkeys and its similar symptoms to smallpox. Other colloquial names that may be used include the bump pox, the human monkeypox, and the swamp pox. Overall, regardless of the term used, Variola minor virus is a serious and potentially life-threatening illness that requires prompt medical attention.