Saint Clairs Disease is a rare neurological disorder that affects the central nervous system, causing various symptoms including muscle weakness, tremors, and problems with coordination. This condition, also referred to as Saint Clair Syndrome or Saint Clair's Syndrome, is characterized by progressive degeneration of nerve cells in the brain and spinal cord. Other synonyms for this disease include Saint Clair Disease, Saint Clairs Syndrome, and Saint Clair Disorder. The condition is named after the Scottish neurologist James St. Clair, who first described it in the early 20th century. Although there is no cure for Saint Clairs Disease, treatments focus on managing the symptoms and improving the patient's quality of life.